Research Overview

Semax is a synthetic heptapeptide derived from the ACTH(4–10) fragment, with a C-terminal Pro-Gly-Pro extension that increases its stability. In laboratory research it serves as a tool compound for studying neuroprotection, neuroplasticity, cognitive processes, BDNF-related pathways and central stress signaling. No therapeutic or clinical claims are made or implied.

Primary Research Areas

• Neuroprotection and neurorestoration: experimental models of ischemia, brain injury and neuronal survival that examine adaptive responses of central nervous system tissue.
• BDNF and neurotrophic signaling: studies of how brain-derived neurotrophic factor and related pathways are regulated in the context of synaptic plasticity, learning and neural adaptation.
• Cognition and attention: behavioral and electrophysiological models assessing memory, focus, information processing and higher cognitive functions.
• Stress and monoaminergic systems: research on dopaminergic and serotonergic signaling and on central responses to acute and chronic stress.

Reconstitution

The lyophilized powder is typically reconstituted with a sterile research solvent such as bacteriostatic water (BAC), which supports handling stability and reduces the risk of contamination.