Research Overview

MOTS-c is a 16-amino-acid mitochondria-derived peptide encoded by the mitochondrial genome. In experimental models it is used to probe metabolic regulation, AMPK-related signaling, mitochondrial function and cellular stress responses.

Primary Research Areas

• Metabolic regulation & AMPK: models examining glucose uptake, insulin sensitivity and AMPK-dependent pathways.
• Mitochondrial function & bioenergetics: studies focused on mitochondrial health, biogenesis and cellular energy homeostasis.
• Cellular stress & oxidative balance: experiments on oxidative stress, cytoprotection and stress-response signaling.
• Exercise-mimetic & aging research: preclinical work exploring exercise-like adaptations and age-related metabolic decline.